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KMID : 0665220040170020138
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Korean Journal of Food and Nutrition
2004 Volume.17 No. 2 p.138 ~ p.146
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Screening of Antioxidative Compounds toward Human Low Density Lipoprotein (LDL) from Useful Plants
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Ryu Beung-Ho
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Abstract
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This study was designed to investigate antioxidative activity of substances isolated from 25 kinds of useful plants resources toward free radical and human low density lipoprotein(LDL). Methanol extracts of Oenothers odorate had the highest antioxidative activity similar with {alpha}-tocopherol. Methanol extracts of Oenothers odorate was extracted again by the ethylacetate. The ethylacetate soluble acidic fraction obtained from methanol extract of Oenothers odorate showed highest activity toward human LDL. Each fraction was purified through Sepadex LH-20 chromatography by elution of chloroform-methanol mixture (90:10 v/v). Fraction, F-2 obtained from Oenothers odorate showed at highest levels of electron donating activity. Fraction, F-2 was identified as 3,4-dihydroxybenzoic acid and 3-hydroxycinnamic acid.
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KEYWORD
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Oenothers odorate, human low density lipoprotein(LDL), 3, 4-dihydroxybenzoic acid, 3-hydroxy-cinnamic acid
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